姓名：王 惠 民  職級：副教授

最高學歷：博士

研究領域：藥學、化學

授課課程：普通化學、有機化學(含實驗)、分析化學(含實驗)、生活化學

分機：561  E-mail：whm5552@ mail.hwai.edu.tw

教育背景

高雄醫學院藥學研究所博士

高雄醫學院藥學研究所碩士

東吳大學化學系學士

學術經歷
中華醫事科技大學 護理系 專任副教授

中華醫事科技大學 長期照顧經營管理系 專任副教授

中華醫事科技大學 製藥工程系 專任副教授

獲獎

105學年度優良教學獎

107年度傑出通識教育教師獎

著作

期刊論文

1. L. C. Chen and H. M. Wang, 1999 “Demonothioacetalization induced by hypervalent iodine and sodium iodine” Org. Prep. Proced Int., 31, 562-564.

2. L. C. Chen, H. M. Wang and I. J. Kang, 1999 “An interrupted Pummerer reaction induced by hypervalent iodine(III) reagent : a new synthesis of pyrrolo[2,1-b]benzothiazole” Heterocycles, 51, 1437-1441.

3. L. C. Chen, I. J. Kang and H. M. Wang, 1999 “Ene reaction with Pummerer-type reaction intermediate of a-(methylthio)isobutyl acetamide : a new synthesis of pellitorine” J. Chin. Chem. Soc., 46(6), 963-966.

4. M. L. Lin, H. M. Wang, I. J. Kang and L. C. Chen, 2000 “Ene reaction with Pummerer-type intermediate of a-(methylthio)-N-methoxyl-N-methyl acetamide : a new synthesis of N-methoxyl-N-methyl-(E,E)-2,4-dienamides” J. Chin. Chem. Soc., 47, 1121-1124.

5. H. M. Wang, H. Y. Huang, I. J. Kang and L. C. Chen, 2001 “An interrupted Pummerer reaction induced by hypervalent iodine(III) reagent : facile synthesis of 2-aryl-1,2-benzisothiazol-3(2H)-ones” Heterocycles, 55, 1231-1235.

6. I. J. Kang, H. M. Wang, C. H. Su and L. C. Chen, 2001 “Synthesis of dienamide natural products using a hypervalent iodine(III) reagent” Chin. Pharm. J., 53, 199-205.

7. I. J. Kang, H. M. Wang, H. Y. Huang and L. C. Chen, 2001 “Facile synthesis of N-substituted isothiazol-3(2H)-ones using a hypervalent iodine(III) reagent” J. Chin Chem. Soc., 48, 1185-1188.

8. H. M. Wang, C. H. Su, I. J. Kang and L. C. Chen, 2002 “Pictet-Spengler condensation of N,N-dimethylsulfamoyl-b-phenethylamines with methylthioacetic ethyl ester. New synthesis of ethyl 1,2,3,4-tetrahydroisoquinoline-1-carboxylates” J. Chin Chem. Soc., 49, 375-378.

9. I. J. Kang , H. M. Wang, C. H. Su and L. C. Chen, 2002 “Synthesis of ethyl 1,2,3,4-tetrahydroisoquinoline-1-carboxylates by Pictet-Spengler condensation using phenyliodine(III) bis(trifluoroacetate)” Heterocycles, 57, 1-4.

10. I. J. Kang, H. M. Wang, M. L. Lin and L. C. Chen, 2002 “Hypervalent iodine(III) mediated synthesis  

   of 2-substituted-5-aryloxazoles” J. Chin. Chem. Soc., 49, 1031-1034.

11. H. M. Wang, I. J. Kang and L. C. Chen, 2003 “Ytterbium triflate-catalysed synthesis of ethyl 1,2,3,4-tetrahydroisoquinoline-1-carboxylates using ethyl chloro(phenylselanyl)acetate” Heterocycles, 60, 1899-1905.

12. H. Y. Huang, H. M. Wang, I. J. Kang and L. C. Chen, 2003 “Ene reaction of Pummerer-type reaction intermediate of (methylthio)acetonitrile : synthesis of dienenitriles” J. Chin. Chem. Soc., 50, 1053-1056.

13. H. Y. Huang, H. M. Wang, I. J. Kang and L. C. Chen, 2003 “Intramolecular sulfenylation using sulfides synthesis of 5H-pyrrolo[1,2-a][3,1]benzothiazines” J. Chin. Chem. Soc., 50, 1057-1060.

14. H. Y. Huang, H. M. Wang, R. S. Hou and L. C. Chen, 2004 “Novel syntheses of 2,3-dihydro-5H-1,4-benzoxathiepins using polymer-supported bis(trifluoroacetoxyiodo)benzene” J. Chin. Chem. Soc., 51, 1025-1028. 

15. H. Y. Huang, R. S. Hou, H. M. Wang and L. C. Chen, 2004 “Hypervalent iodine(III) sulfonate mediated synthesis of imidazo[1,2-a]pyridines” J. Chin. Chem. Soc., 51, 1377-1380.

16. R. S. Hou, H. M. Wang, H. Y. Huang and L. C. Chen, 2004 “Synthesis of imidazo[2,1-a]isoquinolines from a-tosyloxyketones and 1-aminoisoquinoline in ionic liquid solvent” J. Chin. Chem. Soc., 51, 1417-1420.

17. R. S. Hou, H. M. Wang, H. Y. Huang and L. C. Chen, 2004 “Efficient synthesis of imidazo[2,1-a]isoquinolines using a hypervalent iodine(III) sulfonate” Org. Prep. Proced Int., 36(5), 491-494.

18. R. S. Hou, H. M. Wang, Y. C. Lin and L. C. Chen, 2005 “Phenyliodine(III) triflate mediated synthesis of 5-benzoyldihydro-2(3H)-furanones” J. Chin. Chem. Soc., 52(5), 1029-1032.

19. R. S. Hou, H. M. Wang, Y. C. Lin and L. C. Chen, 2005 “Hypervalent iodine(III) sulfonate mediated synthesis of 5-benzoyldihydro-2(3H)-furanone in ionic solvent” Heterocycles, 65(3), 649-656.

20. H. Y. Huang, R. S. Hou, H. M. Wang and L. C. Chen, 2005 “New syntheses of 1-benzoyltetrahydroisoquinoline derivatives using polymer-supported bis(trifluoroacetoxyiodo)benzene” Heterocycles, 65(8), 1881-1887.

21. R. S. Hou, H. M. Wang, H. Y. Huang and L. C. Chen, 2005 “Allylation of Meldrum’s acids by allylic alcohols using tetrakis[triphenylphosphine]- palladium(0) catalysts” Heterocycles, 65(8), 1917-1923.

22. R. S. Hou, H. M. Wang, Y. W. Chang and L. C. Chen, 2006 “Ionic Liquids in organic synthesis: The Pummerer reaction” J. Chin. Chem. Soc., 53(2), 431-435.

23. R. S. Hou, H. M. Wang, H. H. Tsai and L. C. Chen, 2006 “Synthesis of 2-phenylthiazoies from a-tosyloxyketones and thiobenzamide in [Bmim][PF6] ionic liquid at ambient temperature” J. Chin. Chem. Soc., 53(4), 863-866.

24. H. M. Wang, R. S. Hou, H. Y. Huang and L. C. Chen, 2006 “Ionic liquids in organic synthesis: The Pictet-Spengler reaction” Heterocycles, 68(8), 1651-1658.

25. H. Y. Huang, R. S. Hou, H. M. Wang and L. C. Chen, 2006 “Direct a-hydroxylation of aryl ketones using a hypervalent iodine(III) sulfonate” Org. Prep. Proced Int., 38(5), 473-476.

26. H. M. Wang, I. C. Liang, R. S. Hou, H. Y. Huang and L. C. Chen, 2007 “Ionic liquids in organic synthesis: The Pummerer reaction” J. Chin. Chem. Soc., 54(1), 127-130.

27. H. M. Wang, R. S. Hou, J. L. Wu and L. C. Chen, 2007 “Polymer-supported hypervalent iodine reagent mediated synthesis of a-azidoketone” J. Chin. Chem. Soc., 54(5), 1333-1335.

28. H. T. Cheng, R. S. Hou, H. M. Wang and L. C. Chen, 2008 “Hypervalent iodine(III) sulfonate reagent mediated synthesis of 4-aryl-2-phenyloxazoles in ionic liquid” J. Chin. Chem. Soc., 55(4), 919-922.

29. H. Y. Huang, H. M. Wang, R. S. Hou, H. T. Cheng and L. C. Chen, 2008 “Hypervalent iodine(III) sulfonate mediated synthesis of 4 a-thiocynanatoketones in a task-specific ionic liquid [bmim]SCN” J. Chin. Chem. Soc., 55, 1204-1207.

30. P. Y. Lin, R. S. Hou, H. M. Wang, I. J. Kang and L. C. Chen, 2009 “Efficient synthesis of aminothiazoles and fanetizole in liquid PEG-400 at ambient conditions” J. Chin. Chem. Soc., 56(3), 455-458.

31. H. T. Cheng, R. S. Hou, H. M. Wang, I. J. Kang, P. Y. Lin and L. C. Chen, 2009 “Hypervalent iodine(III) sulfonate mediated synthesis of 2-arylimidazo[1,2-a]pyrimidines in liquid PEG-400” J. Chin. Chem. Soc., 56(3), 632-635.

32. P. Y. Lin, R. S. Hou, H. M. Wang, I. J. Kang and L. C. Chen, 2009 “Hypervalent iodine(III) sulfonate mediated synthesis of quinoxalines in liquid PEG-400” J. Chin. Chem. Soc., 56(4), 1-5.

33. P. Y. Lin, R. S. Hou, H. M. Wang, I. J. Kang and L. C. Chen, 2009 “Hypervalent

   Iodine(III) Sulfonate Mediated Synthesis of Quinoxalines in Liquid PEG-400”

   J. Chin. Chem. Soc., 56(4), 683-687.

34. Y. T. Xie, R. S. Hou, H. M. Wang, I. J. Kang and L. C. Chen, 2009 “An efficient protocol for the synthesis of N-alkyl and N-arylimides using the Lewis acidic ionic liquid cholide chloride-2ZnCl₂” J. Chin. Chem. Soc., 56(4), 839-842.

35. J. L. Wu, R. S. Hou, H. M. Wang, I. J. Kang and L. C. Chen, 2009

“Gd(OTf)3–[Bmim][PF6]: A Novel and Recyclable Catalytic System for the

Synthesis of Quinolines” J. Chin. Chem. Soc., 56(5), 867-872.

36. H. M. Wang, R. S. Hou, H. T. Cheng and L. C. Chen, 2009 “An efficient protocol for the Friedlander quinoline synthesis using the Lewis acidic ionic liquid cholide chloride-2ZnCl₂ ” Heterocycles, 78(2), 487-493.

37. Y. L. Chang, C. L. Chung, F. W. Wu, H. M. Wang, R. S. Hou, I. J. Kang and L. C. Chen, 2010 “Iodobenzene-Catalyzed Synthesis of a-Azidoketones and a-thiocyanatoketones from Aryl Ketones with MCPBA as a cooxidant” J. Chin. Chem. Soc., 57(2), 149-152.

38. Y. L. Chang, H. M. Wang, R. S. Hou, I. J. Kang and L. C. Chen, 2010 “Iodobenzene-Catalyzed Synthesis of Imidazo[1,2-a]pyridines from Aryl Ketones with mCPBA in Ionic Liquid” J. Chin. Chem. Soc., 57(2), 153-156.

39. R. S. Hou, H. M. Wang, I. J. Kang, H. D. Du and L. C. Chen, 2010 “The First Cerium(IV) Ammonium Nitrate (CAN)-catalyzed Friedander Synthesis of Quinolines in Ionic Liquid ” Heterocycles, 81(3), 689-698.

40. C. L. Chung, C. H. Han, H. M. Wang, R. S. Hou and L. C. Chen, 2011 “Hypervalent Iodine(III) Reagent Mediated Synthesis of 2-Methylbenzofuran Derivatives by Pummerer-type Reaction in Ionic Liquid” J. Chin. Chem. Soc., 58(1), 90-93.

41. H. M. Wang, R. S. Hou, H. D. Du, I. J. Kang and L. C. Chen, 2011 “Dowex-50W Promoted

   Friedländer Synthesis of Substituted Quinolines under Solvent-free conditions ” Heterocycles,

   83(2), 331-338.

 

國際/國內研討會論文

1. L. C. Chen, H. M. Wang and I. J. Kang, 1999 “Intramolecular sulfenylation using a hypervalent iodine(III) reagent” 第八屆亞洲化學會議 (台灣台北)

2. L. C. Chen, H. M. Wang and I. J. Kang, 2000 “Synthesis of sulfur-containing heterocycles using a hypervalent iodine(III) reagent” 第六屆國際華人有機化學研討會 (大陸上海)

3. I. J. Kang, H. M. Wang and L. C. Chen, 2000 “Ene reaction with Pummerer-type reaction intermediate of 1-[(2methylthio)ethanoyl]piperidine : synthesis of (2E, 4E)-dienamides” 中國化學會 (台灣台中)

4. M. L. Lin, H. M. Wang and L. C. Chen, 2000 “Ene reaction with Pummerer-type reaction intermediate of a-(methylthio)-N-methoxy-N-methyl acetamide : steroselective synthesis of conjugated dienals” 中國化學會 (台灣台中)

5. I. J. Kang, H. M. Wang, C. H. Su and L. C. Chen, 2001 “A new and direct synthesis of 2-substituted-5-aryloxazoles using a hypervalent iodine(III) reagent”中國化學會 (台灣台南)

6. I. J. Kang, H. M. Wang, C. H. Su and L. C. Chen, 2001 “Synthesis of ethyl 1,2,3,4-tetrahydroisoquinoline-1-carboxylates by Pictet-Spengler condensation using phenyliodine(III) bis(trifluoroacetate)”中國化學會 (台灣台南)

7. H. Y. Huang, H. M. Wang, I. J. Kang and L. C. Chen, 2002 “An interrupted Pummerer reaction induced by hypervalent iodine(III) reagent : preparation of 5H-pyrrolo[1,2-a][3,1]benzothiazines” 第七屆國際華人有機化學研討會 (台灣新竹)

8. H. Y. Huang, H. M. Wang and L. C. Chen, 2003 “Novel syntheses of 2,3-dihydro- 5H-1,4-benzoxathiepins using polymer-supported bis(trifluoroacetoxyiodo)- benzene” 中國化學會(台灣中壢)

9. R. S. Hou, H. M. Wang, Y. C. Lin and L. C. Chen, 2004 “Hypervalent iodine(III) sulfonate mediated synthesis of 5-benzoyldihydro-2(3H)-furanone in ionic solvent” 中國化學會(台灣台中)

10. H. Y. Huang, R. S. Hou , H. M. Wang and L. C. Chen, 2005 “Syntheses of 1-acyl-1,2,3,4-tetrahydroisoquinoline derivatives in ionic liquid solvent” 中國化學會(台灣高雄)

11. H. M. Wang, I. C. Liang, R. S. Hou, H. Y. Huang and L. C. Chen, 2006 “Phenyliodine(III) bis(trifluoroacetate) mediated synthesis of 2-aryl-1,2-benzisothiazol-3(2H)-ones in ionic solvent” 中國化學會(台灣台北)

12. 黃信裕，李淑惠，王惠民，洪永潤，項怡平 2019 “南部某醫事大學學生對用

   藥安全觀點之分析探討” 社團法人臺灣臨床藥學會(台灣台北)

專書/展出

1. 洪耀釧，孫逸民，莊尊仁，王惠民，王豐益，2004 “有機化學” 學銘圖書有限公司。 2. 王惠民，胡隆傑，王力行，薛光華，解熙英，陳柏衣，2010 ”基礎自然科學”    新文京開發出版股份有限公司 3. 王惠民，羅文瑞，楊天賜，2023 “基礎化學” 華格那企業有限公司。